Tosylation (TsCl): Turning OH into a Leaving Group: Mechanism + Exam Traps
Convert alcohols to tosylates (OTs) using TsCl/pyridine: preserves C–O bond stereochemistry and sets up SN2/E2 reactions without carbocations.
Reaction: Tosylation (TsCl): Turning OH into a Leaving Group
What it does: Convert alcohols to tosylates (OTs) using TsCl/pyridine: preserves C–O bond stereochemistry and sets up SN2/E2 reactions without carbocations.
Typical reagents: TsCl, pyridine
Key intermediate: Varies / context-dependent
Driving force: Formation of more stable bonds / products