Synthesis Decision Tree: SN1/SN2/E1/E2 (Pick the Path Fast): Workflow + Practice

A synthesis-focused decision tree: given a substrate + reagent + solvent, predict substitution vs elimination and major product.

  • Reaction: Synthesis Decision Tree: SN1/SN2/E1/E2 (Pick the Path Fast)
  • What it does: A synthesis-focused decision tree: given a substrate + reagent + solvent, predict substitution vs elimination and major product.
  • Typical reagents: NaOEt, EtOH, Δ (decision example)
  • Key intermediate: Carbocation
  • Driving force: Formation of more stable bonds / products
  • Exam type: Choose reagents
  • Exam type: Plan order of operations
  • Exam type: Chemoselectivity

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