Retrosynthesis: Alkene Disconnections (Olefination vs Elimination): Workflow + Practice

When you see an alkene in the target, ask: was it made by elimination (E2/E1) or by carbonyl olefination? This page teaches the decision logic.

• Reaction: Retrosynthesis: Alkene Disconnections (Olefination vs Elimination)
• What it does: When you see an alkene in the target, ask: was it made by elimination (E2/E1) or by carbonyl olefination? This page teaches the decision logic.
• Typical reagents: Retrosynthesis: alkene ← carbonyl + Wittig/HWE
• Key intermediate: Phosphorus ylide / betaine
• Driving force: Formation of more stable bonds / products
• Exam type: Choose reagents
• Exam type: Plan order of operations
• Exam type: Chemoselectivity