pKa and Basicity: Using Acid–Base to Predict Mechanisms: Mechanism + Exam Traps
Use pKa and acid–base logic to predict proton transfer steps, leaving group activation, and whether nucleophiles behave as bases vs nucleophiles in common…
Reaction: pKa and Basicity: Using Acid–Base to Predict Mechanisms
What it does: Use pKa and acid–base logic to predict proton transfer steps, leaving group activation, and whether nucleophiles behave as bases vs nucleophiles in common…
Typical reagents: NaH (base)
Key intermediate: Varies / context-dependent
Driving force: Formation of more stable bonds / products