MS Fragmentation Patterns — The High-Yield Cleavages: Mechanism + Exam Traps
Once you have the molecular ion and halogen clues, fragments tell you what substructures are present: benzylic cleavage, α-cleavage next to heteroatoms,…
Reaction: MS Fragmentation Patterns — The High-Yield Cleavages
What it does: Once you have the molecular ion and halogen clues, fragments tell you what substructures are present: benzylic cleavage, α-cleavage next to heteroatoms,…
Typical reagents: EI-MS fragmentation (analysis)
Key intermediate: Oxonium ion
Driving force: Formation of more stable bonds / products