Mass Spectrometry Basics — Molecular Ion, Isotopes, Fragments: Mechanism + Exam Traps

MS gives molecular weight (M⁺) and fragment clues. High-yield: isotope patterns for Cl/Br, base peak vs molecular ion, and common cleavage rules.

  • Reaction: Mass Spectrometry Basics — Molecular Ion, Isotopes, Fragments
  • What it does: MS gives molecular weight (M⁺) and fragment clues. High-yield: isotope patterns for Cl/Br, base peak vs molecular ion, and common cleavage rules.
  • Typical reagents: EI-MS (analysis)
  • Key intermediate: Varies / context-dependent
  • Driving force: Relief of ring strain / formation of stronger bonds
  • Exam type: Interpret data
  • Exam type: Identify functional groups
  • Exam type: Structure constraints

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