Hydroboration–Oxidation: Anti‑Markovnikov Hydration with Syn Addition

Hydroboration–oxidation adds water to alkenes anti‑Markovnikov with syn stereochemistry. Use the interactive scrubber to master regio/stereo rules, then practice with exam questions.

  • Overall transformation: Alkene → alcohol (anti‑Markovnikov hydration)
  • Reagents: 1) BH3·THF (or 9‑BBN) 2) H2O2, NaOH
  • Regiochemistry: OH ends up on less substituted carbon
  • Stereochemistry: Syn addition of H and OH (stereospecific)
  • Rearrangements: None
  • Exam type: Predict the major product
  • Exam type: Regiochemistry
  • Exam type: Stereochemistry

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