Grignard Reagents: Core Reactivity Patterns: Mechanism + Exam Traps

A concise map of Grignard reactivity: as strong nucleophiles/bases, what they add to, common workups, and what functional groups destroy them.

  • Reaction: Grignard Reagents: Core Reactivity Patterns
  • What it does: A concise map of Grignard reactivity: as strong nucleophiles/bases, what they add to, common workups, and what functional groups destroy them.
  • Typical reagents: 1) CH3MgBr (ether) 2) H3O+
  • Key intermediate: Varies / context-dependent
  • Driving force: Formation of more stable bonds / products
  • Exam type: Predict major product
  • Exam type: Mechanism choice

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