Carboxylic Acid Derivative Interconversion Map (Reactivity Ladder): Mechanism + Exam Traps

The canonical Orgo II map: acid chlorides, anhydrides, esters, amides, and carboxylic acids.

• Reaction: Carboxylic Acid Derivative Interconversion Map (Reactivity Ladder)
• What it does: The canonical Orgo II map: acid chlorides, anhydrides, esters, amides, and carboxylic acids.
• Typical reagents: NH3 (amide formation example)
• Key intermediate: Acyl intermediate
• Driving force: Formation of more stable bonds / products
• Exam type: Choose reagents
• Exam type: Plan order of operations
• Exam type: Chemoselectivity