Alcohol → Amine: The Canonical Routes (Tosylate/Mesylate, Azide, SN2): Workflow + Practice
Students constantly need 'turn an alcohol into an amine.
- Reaction: Alcohol → Amine: The Canonical Routes (Tosylate/Mesylate, Azide, SN2)
- What it does: Students constantly need 'turn an alcohol into an amine.
- Typical reagents: 1) TsCl, pyridine 2) NaN3 3) LiAlH4, H2O (or H2/Pd)
- Key intermediate: Carbocation
- Driving force: Formation/capture of a stabilized cation
- Exam type: Choose reagents
- Exam type: Plan order of operations
- Exam type: Chemoselectivity