Alcohol → Amine: The Canonical Routes (Tosylate/Mesylate, Azide, SN2): Workflow + Practice

Students constantly need 'turn an alcohol into an amine.

  • Reaction: Alcohol → Amine: The Canonical Routes (Tosylate/Mesylate, Azide, SN2)
  • What it does: Students constantly need 'turn an alcohol into an amine.
  • Typical reagents: 1) TsCl, pyridine 2) NaN3 3) LiAlH4, H2O (or H2/Pd)
  • Key intermediate: Carbocation
  • Driving force: Formation/capture of a stabilized cation
  • Exam type: Choose reagents
  • Exam type: Plan order of operations
  • Exam type: Chemoselectivity

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