Protect alcohols as TBDMS (TBS) ethers (TBDMSCl + base) and remove them (TBAF or acid) to control multi-step synthesis without unwanted reactions.
Reaction: Alcohol Protecting Groups: TBDMS (TBS) Ethers and Deprotection
What it does: Protect alcohols as TBDMS (TBS) ethers (TBDMSCl + base) and remove them (TBAF or acid) to control multi-step synthesis without unwanted reactions.
Typical reagents: TBDMSCl, imidazole
Key intermediate: Varies / context-dependent
Driving force: Formation of more stable bonds / products